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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK13 All Species: 21.52
Human Site: Y343 Identified Species: 43.03
UniProt: O15264 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15264 NP_002745.1 365 42090 Y343 D E W K Q H I Y K E I V N F S
Chimpanzee Pan troglodytes Q9N272 365 41989 Y343 D E W K Q H I Y K E I V N F S
Rhesus Macaque Macaca mulatta XP_001112462 367 41940 K346 E W K R V T Y K E V L S F K P
Dog Lupus familis XP_850384 366 42002 Y343 D E W K Q H I Y K E I V N F S
Cat Felis silvestris
Mouse Mus musculus Q9Z1B7 366 42053 Y343 D E W K Q H I Y K E I S N F S
Rat Rattus norvegicus Q9WTY9 366 42032 Y343 D E W K Q H I Y K E I A N F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509537 374 42522 Y343 E E W K S H I Y K E I T S F S
Chicken Gallus gallus P79996 382 43990 I356 I E E W K E L I Y K E V M D W
Frog Xenopus laevis P47812 361 41700 K339 E L D I E E W K R L T Y E E V
Zebra Danio Brachydanio rerio Q9DGE2 361 41614 K339 E L D I E E W K R Q T Y E E M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61443 365 42080 V344 V E K W R E M V F S E V T A F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17446 377 43900 E354 E W K K I I W E E I S D F Q K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.2 64.8 93.9 N.A. 92.9 91.8 N.A. 84.7 44.7 59.7 60 N.A. 56.4 N.A. 51.1 N.A.
Protein Similarity: 100 97.5 78.4 97.2 N.A. 97.2 96.1 N.A. 91.4 63.6 75.8 76.9 N.A. 73.1 N.A. 72.4 N.A.
P-Site Identity: 100 100 0 100 N.A. 93.3 93.3 N.A. 73.3 13.3 0 0 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 93.3 93.3 N.A. 86.6 33.3 20 26.6 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 42 0 17 0 0 0 0 0 0 0 0 9 0 9 0 % D
% Glu: 42 67 9 0 17 34 0 9 17 50 17 0 17 17 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 17 50 9 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 17 9 9 50 9 0 9 50 0 0 0 0 % I
% Lys: 0 0 25 59 9 0 0 25 50 9 0 0 0 9 9 % K
% Leu: 0 17 0 0 0 0 9 0 0 9 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 42 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % P
% Gln: 0 0 0 0 42 0 0 0 0 9 0 0 0 9 0 % Q
% Arg: 0 0 0 9 9 0 0 0 17 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 9 0 0 0 0 9 9 17 9 0 50 % S
% Thr: 0 0 0 0 0 9 0 0 0 0 17 9 9 0 0 % T
% Val: 9 0 0 0 9 0 0 9 0 9 0 42 0 0 9 % V
% Trp: 0 17 50 17 0 0 25 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 9 50 9 0 0 17 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _